FORMULATION AND EVALUATION OF ATENOLOL SUSTAINED RELEASE TABLETS BY USING NATURAL POLYMERS

The aim of present study was to develop sustained release tablet of atenolol by using natural polymers. Physicochemical properties of gum Moringa oleifera was studied like loss on drying, pH,viscocity, Sustained tablet of atenolol was prepared by using gum Moringa oleifera, Gaur Gum, Xanthan Gum in various concentrations by direct compression using 8 mm concave punch. Precompresion parameter was studied. All the observations are within the prescribed limits. Prepared Atenolol tablets were evaluated for post compression parameters which are in acceptable ranges. Ts no interaction found between any excipient and drug. Keywords: Atenolol, Moringa oleifera gum, Guar gum, Xanthan gum, Sustained release tablets.