Effect of Glycaemic Control on Quality of Life(HRQoL) in Diabetes

INTRODUCTION: Intensified glycaemic control is recommended in diabetes type 2 patients as it prevents or postpones chronic diabetic complications, but its effect on quality of life in the short and long term is still not clear. AIMS: To study effect of various anti diabetic treatment regimens on level of glycaemic control and Quality of life in patients of type 2 diabetes mellitus. MATERIALS AND METHOD: Patients with type 2 diabetes mellitus aged 30-70 years of either gender on oral anti-diabetic therapy for at least 1 year were enrolled. After taking written informed consent, patients were interviewed according to a pre-validated questionnaire regarding quality of life and responses along with investigations and treatment given were noted in the performa. Data obtained was analysed using percentage, mean, standard deviation and unpaired t tests. RESULTS:A total of 48 patients were enrolled. Patients were assigned to one of the three groups depending on number of anti-diabetic drugs prescribed. Fasting blood sugar was better controlled in patients taking one anti diabetic drug. Overall Quality of life was better in patients on dual drug therapy while overall impression in comparison to first visit to OPD was significantly better in patients on triple drug therapy from monotherapy and dual drug regimen patients. CONCLUSION: Overall Quality of life was better in patients on dual drug therapy while overall impression in comparison to first visit to OPD was significantly better in patients on triple drug therapy from monotherapy and dual drug regimen patients.