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ANTI-TUBERCULAR ACTIVITY OF SYNTHESIZED NOVEL 2,5-DISUBSTITUTED-1,3,4-OXADIAZOLE DERIVATIVES
Journal: Indian Drugs (Vol.52, No. 2)Publication Date: 2015-02-25
Authors : Ega D.; Attari Z.; Mudgal J.; Bairy I.; Vishnuprasad S.; Nampurath G. K.;
Page : 40-44
Keywords : ;
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Abstract
A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.
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