Early Postnatal Stress Impacts Brain Development

Early postnatal stress can affect the development of the Hypothalamic- Pituitary-Adrenal (HPA) axis, and cause psychopathology later in life. This mini-review briefly mentions the concept of developmental origins of health and disease. HPA axis alteration, psychopathology, and epigenetic modifications following early postnatal stress are also discussed. Finally, the clinical importance of coexistence of early postnatal seizure and stress are emphasized.