NANO-DISPERSIONS (SUSPENSIONS): AN EMERGING TRENDIN ENHANCING DRUG SOLUBILITY AND DRUG TARGETING
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 09)Publication Date: 2017-09-07
Authors : Kousar Begum; Sathyabratha Jena; Konatham Monika; B.Jagadeesh Babu; M.Reshma; A.Aravanthi;
Page : 2833-2844
Keywords : Nano technology; nano suspension; classification; methods of preparation; evaluation parameters;
Abstract
Nano technology is an innovation for the drug targeting to release the drug in short duration of time at a specific site. Nano sized particles are having the more dissolution velocity to increase the drug action and these are majorly useful for the poorly solubilised drugs to increase its solubility and enhance the bio availability. This article explains about the nanosuspensions, in which drug particles are distributed uniformly throughout the vehicle. Which exhibit its maximum solubility and ready to use through any route of administration? Recently nanosuspensions are ment for oral route for administration. This review explains about the stability of nano suspensions compared to other oral liquid dosage forms, classification, methods of preparation with its major advantages, limitations, properties of nanosuspensions, evaluation methods and its pharmaceutical applications. Key words: Nano technology, nano suspension, classification, methods of preparation, evaluation parameters
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