STUDYING THE POLYPHENOLIC STRUCTURE OF LAURUS NOBILIS L. LEAVES
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 09)Publication Date: 2017-09-07
Authors : Elena T. Zhilyakova; Oleg O. Novikov; Dmitriy I. Pisarev; Anastasiya Y. Malyutina; Nikolay N. Boyko;
Page : 3066-3074
Keywords : bay laurel; highly effective liquid chromatography; flavonoids; hyperoside; method of absolute graduation;
Abstract
In work research results of the polyphenols chemical composition of Laurus nobilis L leaves are presented. Bay laurel is a known food plant having also wide range of important pharmacological properties such as: hypoglycemic, anti-inflammatory, antiepileptic and antioxidant. Using a method of a highly effective liquid chromatography in the gradient mode of elution, the structure of flavonoids of a plant which includes 12 components which are glycosides of quercetine and kaempferol is established. The technique of quantitative definition of flavonoids in raw materials of bay laurel in terms of hyperoside, consisting in application of a method of absolute graduation is developed. The maintenance of hyperoside in raw materials made 0.211%±0.01. Keywords: bay laurel, highly effective liquid chromatography, flavonoids, hyperoside, method of absolute graduation
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