EPIDEMIOLOGICAL CHARACTERISTICS OF HIV INFECTION IN THE REPUBLIC OF MARI EL

This paper deals with the analysis of the incidence of the disease caused by the human immunodeficiency virus (HIV infection), the dynamics of the incidence of this nosology have been traced, and the HIV-incidence of the population of the Republic of Mari El (RME) has been characterized in comparison with this indicator in the Russian Federation (RF). HIV is a socially significant disease, tends to increase in cases both in the RME and in the Russian Federation. This issue is a matter of concern and has been under consideration at the state level. In 2016, the Government of the Russian Federation approved the State Strategy for Counteracting the Spread of HIV Infection in Russia for the period to 2020 and further prospects. Implementation of this strategy requires a detailed approach, taking into account modern technologies, the capabilities of which should be used in an accurate and step-by-step manner. The study analyzed the epidemiological maps of the patients of the state budgetary institution of the Republic of Mari El “Republican Center for the Prevention and Control of AIDS and Infectious Diseases” (SBI RME RCPC AIDS and ID), calculated the incidence and prevalence of the population of the Republic using statistical methods (calculations of relative and average values, building of dynamic series and estimation of statistically significant differences), used graphicalanalytical methods and a retrospective epidemiologic analysis. According to the results of the study for the period 2007-2016, an increase in the incidence of 2.2 times was revealed in the RME. The cumulative number of HIV-positive patients in the RME during the study period increased 3.3 times. The prevalence index in 2016 in the RME is 1.7 times lower than the Russian average. The results of the study will help to conduct a comprehensive epidemiological diagnosis of the situation of HIV incidence in the RME, including mathematical simulation of the prognosis of the HIV incidence and prevalence of the population, which will allow diversifying approach to creating a "single preventive space" on the territory of the republic. Keywords: HIV infection, preventive space, epidemiological analysis, incidence