Asymptomatic bacteriuria in type 2 diabetic women patients who are attending Medicine OPD of Government Dharmapuri Medical College, Dharmapuri

Introduction: Infection is a leading cause of hospitalization among diabetic patients. Diabetes is associated with increased risk of developing infection increased severity of infection and prolonged hospital stay. Urinary tract infection, respiratory tract infection and soft tissue infection are common infections with increased incidence of diabetes. Altered host defenses, vascular abnormalities, frequent hospital admissions are responsible for increased incidence. Aim of the study: To find out the prevalence of Asymptomatic Bacteriuria in type 2 diabetic women, to analyze the spectrum of organisms responsible for Asymptomatic Bacteriuria in this group and its antimicrobial sensitivity pattern. Materials and methods: There was 164 participants in the study group and 56 non-diabetic women in the control group GROUP-I: Women with type 2 diabetes were recruited randomly from the Female patients of General Medicine OPD and Diabetic OPD, Government Dharmapuri Medical College Hospital, Dharmapuri. GROUP-II: Women without diabetes were selected randomly from the general population. They were relatives and friends of inpatients admitted in general medical ward. The following laboratory data were included: fasting plasma glucose, blood urea, serum creatinine, albuminuria, glycosuria, and leucocyturia. These patients were evaluated for microvascular and macrovascular complications of diabetes. Results: Overall the prevalence of ASB was 22.56% in the study group and 5.36% in control group. Conclusion: Asymptomatic bacteriuria was significantly more among diabetics with nephropathy. Simple bedside method to screen asymptomatic bacteriuria is leucocyturia and it has a positive predictability (72.7%) to detect bacterial isolates. Among asymptomatic bacteriuria, gram-negative isolates were greater than gram-positive ones Isolates were resistant to most of the commonly used antimicrobials (Ciprofloxacin, Ofloxacin, Gentamicin, and Cefotaxime) in clinical practice.