FREQUENCY AND OUTCOME OF DYSLIPIDEMIA IN DIABETIC FOOT PATIENTS WITH TYPE-II DIABETES MELLITUS

Objective: The objective of this study was to determine the frequency and outcome of dyslipidemia in diabetic foot patients with type-2 diabetes mellitus Material & Methods: This descriptive case series study was carried out in the department of Medicine, Liaquat University Hospital and Jamshoro/Hyderabad, From January 2010 to July 2010. Total 196 patients were included in the study with age range > 40 years, known/diagnosed cases of diabetes mellitus (type 2), patients with clinical and radiographic diagnosis of diabetic foot; either gender or having abnormal lipid profile were included. Patients of known or newly diagnosed cases of type 2 diabetes mellitus (DM) admitted with history of wound in lower limbs, confirmed on physical examination, measuring Ankle to Brachial Pressure Index (ABI) and Doppler ultrasound examination were evaluated for grading of ulcer using Wagner's classification. Patients fulfilling the inclusion criteria were worked up for the dyslipidemia by sending blood sample for fasting lipid profile. The data was collected on predesigned Performa. Results: Mean age was found 55.2+4.8 years. Male were found in the majority 65.3%. According to the presenting features in the skin redness was found most common 71.42%, pain during walking found in 57.14% cases, as well as weak pulse was noted in 43.88% of the cases. Majority of the cases were found with abnormal lipid profile 55.11%. Dyslipidemia were found with significant difference in gangrenous diabetic foot as well as grade IV and grade V of Wagner's classification p value 0.001. Mortality was not found because gangrenous diabetic foots was referred to orthopaedic department for imputation. Conclusion: We concluded that dyslipidemia was 55.11% and it has an important role in development of severity of diabetic foot. Diabetic patients should performed lipid profile for early check of dyslipidemia to reduce the morbidity and mortality. Key words: Diabetes mellitus, dyslipidemia, diabetic foot