Benign neural tumours: a clinico-pathologic study

Peripheral nerve sheath tumors include a spectrum of diseases ranging from benign to malignant entities. They include schwannoma, neurofibroma, malignant peripheral nerve sheath tumors, neurothekeoma, perineurioma, granular cell tumour, mucosal neuroma, and palisaded encapsulated neuroma. Schwannoma is a slow growing tumour derived from the neuroectoderm originating from the Schwann cells of the peripheral neural sheath, most commonly involving the VIII cranial nerve. Other sites in the body can also be affected. Neurofibroma is also a slow-growing tumour and can involve multiple sites. It can have a genetic predisposition. Definitive diagnosis requires histopathological confirmation. Immunohistochemical marker S-100 is confirms the diagnosis.