Novel Transfusion parameters in Blood bank for Thalassemia patients

Introduction: Thalassemia major is most common monogenic disorder in the world. Around 1,00,000 children are born each year with the severe b homozygous state of the disease in India. The objectives of this study was to assess clinical data and novel transfusion parameters of Thalassemia major patients attending tertiary care hospital. This was undertaken as very few studies have been done in this region of the country. Materials and Method: The study was done at a tertiary care teaching hospital from January 2014 to December 2014. 35 thalassemia major patients who received blood transfusions in the hospital were taken as inclusion. Clinical details, blood transfusion details and novel parameters of transfusion annual blood requirement and its derivatives were collected on proforma for all patients and data interpreted. Result: Males (80%) outnumbered females (20%) with male to female ratio of 4:1. Nearly half of the study population was aged between 10 to 12 years (51.43). Majority of the patients had one blood transfusion per month (91.43%) and were on chelation therapy (71.43%). Novel transfusion parameters which includes Annual blood requirement, Mean Annual pure red cell requirement, Mean Annual iron load and Mean Daily iron loading were calculated for each patient. Conclusion: The present study describes the novel transfusion parameters in blood bank for thalassemia major patients attending the tertiary care hospital and emphasizes on maintenance of transfusion record of thalassemia major patients for better management of these patients.