CURRENT ISSUES OF ETIOPATHOGENESIS, CLINICAL PICTURE, DIAGNOSIS AND TREATMENT OF MULTIPLE SCLEROSIS (LITERATURE REVIEW AND OWN DATA)

The article provides a literature review on contemporary aspects of etiopathogenesis, clinical picture, diagnosis and treatment of multiple sclerosis (MS). MS is one of the most socially significant problems of modern neurology. MS has been proven to be a multifactorial disease, which develops as a result of both internal and external factors. In the early stages of this disease there is damage to the axons, therefore MS is not only considered an autoimmune demyelinating disease, but also neurodegenerative. The disease is characterized by a variety of clinical manifestations. The variety of neurological symptoms is due to a multiplicity of foci of demyelination and their localization in brain and spinal cord. Neuroimaging methods play an important role in the modern diagnosis of MS. Management of patients with a diagnosis of MS involves compulsory and long-term basic therapy with immunomodulatory drugs that change the course of multiple sclerosis.