APPLICATION OF SELECTIVE THROMBOLYTIC THERAPY FOR ISCHEMIC STROKE TREATMENT
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 10)Publication Date: 2017-10-06
Authors : Igor B. Kovalenko Zhanna Yu. Chefranova Nadezhda S. Zueva Vyacheslav D. Polyansky;
Page : 3727-3731
Keywords : ischemic stroke; selective thrombolysis; hemorrhagic conversion; systemic thrombolysis.;
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Abstract
The article deals with the review and analysis of the major study related to both applications of STLT and that compared to systemic thrombolysis which demonstrate good functional results after 90 days of STLT application and less number of intracranial hemorrhage during 24 hours. The comparative analysis of the outcomes of ischemic stroke treatment based on systemic and selective thrombolysis by Actilyse was conducted in Belgorod Regional Clinical Hospital. The procedure of selective thrombolysis was described. The analysis of the effectiveness and complications depending on medication dose and deterioration and thrombolysis period after initial neurological symptoms was conducted. The obtained results proved case fatality decrement and neurological symptoms amendment with patients after endovascular therapy. Key words: ischemic stroke, selective thrombolysis, hemorrhagic conversion, systemic thrombolysis.
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