An Unusual Cause of Melena: Brunner’s Gland Hyperplasia

A 43 year old woman presented melena with severe anemia without particular medical history or medication intake. Esophagogastroduodenoscopy showed a large ulcerative mass located from the first to second portion of the duodenum. Endoscopic ultrasonography and the abdominal computed tomography described a 5cm mass with a tumoral aspect. A gastrointestinal stromal tumor (GIST) was suspected and a partial duodenectomy was performed. Finally the pathological concluded to the diagnosis of Brunner-gland hyperplasia.