Systemic sclerosis and tuberculosis – A case report
Journal: International Archives of Integrated Medicine (IAIM) (Vol.4, No. 10)Publication Date: 2017-10-15
Authors : S. Uma Ganesh Krishnapriya R R. Srinivasan;
Page : 258-261
Keywords : Systemic sclerosis; Tuberculosis; ANA.;
Abstract
Scleroderma is a chronic systemic autoimmune disease of unknown origin characterized by excessive collagen deposition and autoantibodies. Patients with autoimmune diseases are known to develop infections like tuberculosis due to the disease per se and also secondary to immunosuppressive treatment. Mycobacterial infections are also known to induce the development of autoantibodies. We present a case of simultaneous occurrence of interstitial lung disease and pulmonary tuberculosis (BAL positive for AFB) in a patient with features of systemic sclerosis. Antibody profile was done were found to be positive for ANA. She also had most of the classical features of scleroderma on clinical examination thus confirming the diagnosis. A detailed history, clinical examination, radiological examination, bronchoscopy and immunological test helped in the diagnosis of the patient. We highlight the importance of suspicion, careful general examination, radiological assessment and screening tuberculosis patients for autoantibody profile in presence of a multisystem involvement.
Other Latest Articles
- A Rare Case Report of Total Aplasia of Paranasal Air Sinuses with Posterior Fossa Malformation (Dandy Walker)
- Sequential use of clomiphene citrate and human menopausal gonadotropin in anovulatory infertility
- Pattern of dynamic intestinal obstruction in adults
- Study of characteristic of pericardial effusion and to analyze pericardial fluid in various etiologies
- Community based cross sectional study on prevalence of risk factors of type 2 Diabetes Mellitus in adult population residing in urban area of Shahjahanpur, Uttar Pradesh
Last modified: 2017-10-31 17:42:14