In Vitro anti- inflammatory activity of Vitex leucoxylon Linn. leaves by HRBC membrane stabilization

Various functions of hydro alcoholic extract and ethanolic extract of the Vitex leucoxylon Linn. leaves of were screened for anti-inflammatory activity by human red blood cell (HRBC) membrane stabilization method. The prevention of hypotonicity-induced HRBC membrane lysis was taken as a measure of the anti- inflammatory activity. All the fractions showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug prednisolone. However their activities decreased with time.