Renal angiomyolipomas its spectrum of presentation and management

Renal angiomyolipoma once considered a rare benign renal tumour are relatively common these days accounting for 0.3 - 3 percent of all renal masses. Renal angiomyolipomas are recognized as clonal neoplasms with clonal chromosomal aberrations and a common progenitor cell, the perivascular epithelial cells (PEC ). The epitheloid variant is a recently identfied entity, characterized by predominance of PEC and a unique morphologic and immunohistochemical profile. There is accumulating evidence suggesting that renal epitheloidangiomyolipoma is a malignant disease. They can present in the form of spontanious perirenal haemorrhage, small or large asymptomatic renal mass, or symptomatic renal mass mimiking a renal tumor.