Spontaneous Partial Resolution of a Giant Pulmonary Bulla

Spontaneous partial resolution of giant pulmonary bullae occurs infrequently. The pathophysiology responsible for the natural elimination of giant bullae is not known with certainty. We report a patient who experienced spontaneous sub-total regression of his giant bulla following an infection. This observation suggests that airway inflammation and obstruction may play a role in the mechanism for spontaneous resolution and/or regression of giant bullae.