Intralesional corticosteroid injections in treatment for Giant Central Cell Lesion as an alternative for a surgical approach: Case Report in an 11 year old girl

The Giant Central Cell Lesion is a potentially aggressive intraosseous condition that appears exclusively in the upper and lower jaws, and normally in patients 30 years old, or younger. Its potentiality of causing bone and root reabsorption, and tooth displacement, make its occurrence, although rare, significant. The etiology, as well as the treatment of this lesion has been debated over the years within a scholar community that condemns surgical removal as the only potential treatment, while others report the benefits of alternative pharmacological approaches that have provided diverse results. This case study involves a giant central cell lesion that appeared in an 11 year old girl who initially reported having suffered mandibular trauma. The patient underwent a treatment with intralesional corticosteroid injections (triamcinolone acetonide) during 6 sessions, over an eight month period. The patient was monitored during a 2 year period; subsequent X-ray monitoring revealed that the lesion dissipated. The results of this study showed that the use of intralesional corticosteroids is a non-invasive alternative to surgery, especially in connection to the type of patients that normally present this condition.