Tuberculous Granuloma of the Brain

Tuberculous granuloma of the brain is a bacterial infection involved the brain that causes severe morbidity and mortality. The patient in this case presented with repeated attacks of seizures, fever, intermittent loss of conscious and signs of increased intracranial pressure since several months. This case was firstly diagnosed as Glioblastoma Multiform (GBM), but there was a focal calcification inside the lesion that lead the specialist to suspect tuberculosis. The patient was referred to MRI that revealed a low signal intensity lesion with severe edema in the right cerebral hemisphere which mainly involved the frontal, parietal and temporal lobes of the right cerebral hemisphere. After contrast administration, the lesion showed gyral enhancement of the cortical parts of the lesion that is strongly suggesting tuberculous infection. The histopathology confirmed the diagnosis of tuberculous granuloma. The MRI with contrast remains an important imaging modality to assess the tuberculous infection of the brain.