ASSOCIATION OF C-REACTIVE PROTEIN AND ESSENTIAL HYPERTENSION

Objective: To determine the association of C-reactive protein (CRP) and essential hypertension at tertiary care hospital Patients and Methods: All the patients with ≥30 years of age, either gender with essential hypertension for ≥3 years were included in the six months cross sectional study after taking informed consent. The essential hypertension was labeled when the average of multiple systolic BP readings on two or more subsequent visits was consistently ≥140 mmHg on presentation or average of 02 or more diastolic BP measurements on at least 2 subsequent visits was ≥90 mmHg for ≥ 03 months duration. All the hypertensive population was screened and evaluate for serum C-reactive protein by withdrawn of venous blood sample and considered as raised when it was ≥ 06 mg/L. The data saved on pre-designed proforma and analyzed in SPSS 16 while the mean ±SD, frequencies and percentages was calculated. Results: During six months study period total fifty patients with essential hypertension were evaluate for C-reactive protein. The mean ± for age (years) & duration of chronic liver disease (years) for whole population was 56.81±4.95 & 7.92±3.64 respectively. The CRP was raised in 34 (68%) of the patients with male gender predominance 28 (58.8%) while the mean ± SD for CRP in male and female population was 20.75±7.92 and 22.92±8.86 respectively. Conclusion: Increase in blood pressure was significantly associated with raised circulating C-reactive protein in patients with essential hypertension. Keywords: Essential hypertension, C-reactive protein and inflammatory marker