SYNTHESIS OF 5-{(4-AMINO-N-[2-(DIETHYLAMINO)ETHYL]- o-ANISAMIDO-5-YL}-AMINO-3-SUBSTITUTEDIMINO-7- SUBSTITUTEDIMINO-1,2,4,6-TRITHIAZEPINES
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 11)Publication Date: 2017-11-01
Authors : D.T.Tayade R. D. Thombare S.A. Waghmare;
Page : 4492-4496
Keywords : 5-{(4-Amino-N-[2-(diethylamino)ethyl]-o-anisamido-5-yl}-amino-3-phenylimino-7-ethylimino-1; 2; 4; 6- trithiazepine; 4-amino-5-phenyldithiobiureto-N-[2-(diethylamino) ethyl]-o-anisamide; phenylisothiocarbamoylchloride; acetone-ethanol medium;
Abstract
A novel series of 5-{(4-amino-N-[2-(diethylamino)ethyl]-o-anisamido-5-yl}-amino-3-substitutedimino-7- substitutedimino-1,2,4,6-trithiazepines was synthesized by the interactions of 4-amino-5-substituteddithiobiureto-N- [2-(diethylamino)ethyl]-o-anisamides with phenylisothio carbamoyldichloride in acetone-ethanol medium. The structures of all the synthesized compounds were justified on the basis of chemical characteristics, elemental analysis and spectral studies. Keywords: 5-{(4-Amino-N-[2-(diethylamino)ethyl]-o-anisamido-5-yl}-amino-3-phenylimino-7-ethylimino-1,2,4,6- trithiazepine, 4-amino-5-phenyldithiobiureto-N-[2-(diethylamino) ethyl]-o-anisamide, phenylisothiocarbamoylchloride, acetone-ethanol medium
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