IMMUNOLOGICAL PECULIARITIES OF ADAPTATION OF PATIENTS WITH CARDIOVASCULAR DISEASES TO THE NON-REMOVABLE DENTURES ON THE BACKGROUND OF BALNEOLOGICAL IMMUNOCORRECTION

In order to study the immunological aspects of adaptation to the non-removable bridged dentures on the background of cardiovascular pathology, 115 patients of the dental policlinic VolgSMI were examined. The cytokine profile and concentration of immunoglobulins in the gingival fluid were studied at the stages of odontopreparation and prosthetics using the traditional technique and against the background of balneological immunocorrection with Elton. It was established that the patients without immunocorrection during orthopedic treatment have increase in the concentrations of proinflammatory cytokines in their gingival fluid, which indicates active inflammatory processes in the tissues. The use of Elton helps to reduce the inflammatory process in marginal periodontium and shorten the period of adaptation to bridged solid dentures, which is manifested by a decrease in the concentrations of proinflammatory cytokines in the gingival fluid against the background of activation of local secretory immunity of the mucous membranes. Keywords: cardiovascular diseases, dental diseases, fixed prosthetics, cytokines, immunocorrection.