Localized and Recurrent Angioedema of the Lips Successfully Treated with a Radiofrequency Device

Angioedema is characterized by swelling of the deeper layerof the skin and/or the submucosa. It is usually localized, sudden,and transient, lasting from several hours to a few days and is oftenrecurrent. The swellings develop from extravasation of plasma inthe affected areas because of a transient increase in endothelialpermeability caused by vasoactive substances produced locally [1].Histopathologically, it presents as localized dermal edema withseparation of collagen fibers and dilated venules with endothelialswelling, along with the presence of variable number of lymphocytes,eosinophils and neutrophils [2]. In this study, we report the effect ofa radiofrequency (RF) device on localized and recurrent angioedemaon the lips.