DCIS Breast Arising in a Fibroadenoma - Case Report of an Uncommon Condition

Introduction: Fibroadenoma (FA) is a type of benign tumor that occur in young women below the age of 35 years old. The incidence of carcinoma arising with FA is rare with range of 0.002-0.1% Most cases are detected at an early stage; cases of locally advanced carcinoma with distant metastasis have been published. Case presentation: We present a case of Ductal Carcinoma in situ (DCIS) with microinvasion arising within Fibroadenoma which was being followed for 9 years. Discussion: Fibroadenoma is typically considered to be a type of benign lesion and requires careful observation. However, data regarding whether FA is a risk factor for carcinoma is inconsistent. The present case showed that FAs containing foci of carcinoma in situ can be indistinguishable from benign lesions with imaging, therefore, despite the incidence of carcinoma within FA is estimated at 0.002– 0.1%, it should be considered a long-term risk factor for invasive breast cancer. Complex FA has a higher risk. High degree of suspicion is needed, as there are limitations in screening, which adds to the problem of delayed diagnosis. Conclusions: The present case was reported to increase awareness that Fibroadenoma in the middle and older age group can harbor cancer; early intervention in this age group is suggested.