Acute Liver Failure by Autoimmune Hepatitis (AIH) and Liver Cirrhosis in Adolescent Patient: Case Report

Autoimmune hepatitis (AIH) is defined as chronic liver parenchyma inflammation of unknown etiology. In pathogenesis are involved environmental triggers and immunological tolerance in genetically predisposed patients resulting in liver parenchymal attack by T lymphocytes. For diagnosis, histologic features and specific analytic are required (hypergammaglobulinemia and specific autoantibody), disease is classified as type 1 (ANA and/or SMA and/ or SLA positive) and type 2 (LKM-1 and/or LC1 positive).In few cases AIH remission is acquired, main goal of treatment is to modify natural history, relieve symptoms, improve biochemical parameters and decrease liver tissue inflammation and fibrosis. We report a 19 years old female with acute liver failure secondary to relapse autoimmune hepatitis and liver cirrhosis with a clinical course of 16 years in maintenance treatment with prednisone who presented multiple complications.