Conventional and Targeted Therapy in Metastatic Colorectal Cancer

Colorectal cancer is one of the leading causes of cancer related mortalities and its dismal prognosis is well known. 20% to 25% of colorectal cancer patients have advanced stage disease and systemic chemotherapy is the main treatment for these patients for palliation. But there is a novel treatment option for metastatic colorectal patients. With these novel options median survivals have prolonged from 12 months to nearly 40 months. In this review, we discussed the conventional treatments and new therapy approaches for metastatic colorectal cancer patients.