HEREDITARY MOTOR AND SENSORY NEUROPATHY (HMSN) DISEASE -IN TWO SIBLINGS

Hereditary motor sensory neuropathy (HMSN), also known as Charcot-Marie-Tooth Disease, is an inherited, progressive disease of the nerves with weakness and numbness more pronounced in the legs than the arms. Parts of the nerve cells deteriorate. The muscles in the hands and feet get weak because they no longer receive normal impulses from the nerves, and therefore are not being used adequately. Symptoms vary greatly. In addition to muscle weakness, there can be fatigue, pain, numbness, lack of balance, sight and hearing. There can be high arched feet, hammer toes, foot drop, and foot deformities, and possibly scoliosis. This disorder has been scarcely reported in the Indian literature. Here we report 2 such cases from one family who presented to pediatric department of M.K.C.G medical college with complains of progressive weakness in lower limbs