Preparation of Quantum Dots and Fluorescent Molecularly Imprinted Composite Microspheres for Determination of Tyramine

The CdSe/ZnS core-shell quantum dots were prepared by using liquid paraffin as the reaction solvent and oleic acid as the modifier at a lower cost and temperature by “one-pot shelling” method. The finding of the current work showed that the UV absorption peak of the QDs was at 540 nm and the fluorescence emission peak was 552 nm. The fluorescence production rate can reach up to 32.31%. Also, the fluorescent molecularly imprinted composite microspheres capped with CdSe/ZnS core-shell quantum dots were arranged in the tyramine molecularly imprinting system. Those prepared microspheres exhibited a better selective absorption ability of molecular imprinting and excellent fluorescence properties of quantum dots. It revealed a good linear relationship of the Stern-Volmer curve in the determination of tyramine, the regression equation was in (F0/F) = 0.1092[C] - 0.0046, which indicated that the prepared composite microspheres exhibited better performance. The above results indicate that this method is expected to achieve a fast and accurate detection of tyramine.