Normal Pressure Hydrocephalus Secondary to Intracranial Mass: A Case Series

Background: Normal pressure hydrocephalus is a rare type of communicating hydrocephalus. The symptoms of NPH consist of a triad of gait disturbances, urinary incontinence, and progressive decline in mental function. The definitive treatment is Ventriculo-peritoneal shunt. Case Description: We would like to present a case series, consisting of two cases, of patients who were diagnosed with an intracranial tumor with co-existing symptoms of normal pressure hydrocephalus. In both cases, the CSF protein content was raised and patient's symptoms improved after placement of ventriculo-peritoneal shunt. Conclusion: We believed that increased protein content in CSF in some patients with CNS tumors, might cause NPH by impairing CSF reabsorption at the level of the arachnoid granulations. The association of NPH secondary to CNS tumor and increased CSF protein content should be further evaluated.