Evaluation of analgesic activity of Emblica officinalis in albino rats
Journal: International Journal of Basic & Clinical Pharmacology (Vol.3, No. 2)Publication Date: 2014-04-01
Authors : Bhomik Goel Nishant Pathak Dwividendra Kumar Nim Sanjay Kumar Singh Rakesh Kumar Dixit Rakesh Chaurasia;
Page : 365-368
Keywords : Emblica officinalis; Amla; Anti-nociceptive; Pain; Analgesic; Hot plate method;
Abstract
Background: Amla is one of the most often used herbs in indigenous medicine, whose all parts including fruit, seed, leaves, root, bark, and fl owers are used in various Ayurvedic/Unani medicines. However, studies to establish analgesic potential of amla were limited, so the purpose of the present study was to evaluate analgesic activity of amla, if it possesses any. Methods: Albino rats were divided randomly in three groups of six rats each. Group 1 (control) received distilled water orally, Group 2 (test) received Emblica officinalis extract in dose of 600 mg/kg orally and Group 3 (standard) received Pentazocine in dose 10 mg/kg intraperitoneally. Results: Emblica officinalis extract did not produced statistically significant (p>0.05) analgesia when compared with the control group in hot plate latency, but produced a statistically significant reduction in 6% NaCl induced abdominal writhing (p
Other Latest Articles
- Effect of vitamin D on atorvastatin induced blood sugar changes in Wistar albino rats
- A study to evaluate antioxidant and hepatoprotective activity of aqueous extract of roots of Valeriana wallichii in CCl4 induced hepatotoxicity in rats
- Efficacy of drugs in controlling microalbuminuria of diabetic nephropathy
- Drug use evaluation of cotrimoxazole prophylaxis in people living with human immunodeficiency virus/acquired immune deficiency syndrome at Jimma University Specialized Hospital, Jimma, South West of Ethiopia, 2013
- Drug utilization pattern of antiseizure drugs and their adverse effects in the pediatric population, in a tertiary care hospital attached to a medical college
Last modified: 2014-04-01 23:00:40