Role of Peroxisome Proliferator Activated Receptor Alpha (PPARA) rs4253778 Polymorphism in Endurance Phenotype

An individual's athletic performance is determined with the intersection of the genetic endowment that he/she owns, and its interaction with environmental factors such as training, nutrition, mentoring and sleeping[1]. Around 70% of the variance in athletic performance is explained by genetic factors. Environmental factors play crucial roles in effecting the expression of several genes; and all of these subjects are examined under the topic of epigenetics. As of today, a total of 250 genes are considered to have effect on human performance, and the number seems to increase as we have the new molecular high-through put techniques that are introduced to molecular genetics, it is now possible to analyse hundreds of SNPs in only on application.