The Prefrontal Cortex: A Basic Embryological, Histological, Anatomical, and Functional Guideline

The prefrontal cortex (PFC) unites, processes and controls the information coming from cortex and subcortical structures, and decides and executes goal-oriented behavior. A major function of PFC is to maintain the attention. Furthermore, it has many other functions including working memory, problem solving, graciousness, memory, and intellectuality. PFC is well developed in humans and localized to the anterior of the frontal lobe. This article presents a systematic review and detailed summary of embryology, histology, anatomy, functions and lesions of PFC.