A comprehensive study on effect of collagen dressing in diabetic foot ulcer

Introduction: Wounds can cause painful lengthy hospital stay, multiple stages of surgeries, and enormous financial burden. Biological dressing's collagen granule dressing has advantage over conventional dressing in terms of non-immunogenic, non-pyrogenic, being natural, easy application and decreased days of healing. Objectives: To compare the efficacy and safety of collagen granule dressings and conventional dressing in diabetic wounds in terms of reduced healing time, number of dressing, healing quality and complications Materials and methods: A prospective study was done in which 30 patients who presented with diabetic wounds were chosen by random sampling technique, and were grouped into 2 groups consisting of 15 patients. Thirty patients with foot ulcer were evaluated. A collagen or conventional dressings were applied, and the patients were followed as per standard post-application treatment protocol. Patients underwent dressing changes every day until wound healing or for maximum period of 12 weeks. Changes in wound size were recorded when the dressing was removed; and at 4 and 12 weeks. Conclusions: Our study is a hospital based case control prospective study done in 30 patients of chronic diabetic foot ulcers. There was statistically significant difference between the results of collagen and saline dressings as collagen dressings had better healing response rate as compared to placebo when given along with standard treatment of diabetic foot ulcer.