The “Placebo / Nocebo Effect”: Learning the Impact of Positive / Negative Emotion (S) on the Physiology of Human Cells

Placebo effect is an epidemic phenomenon observed in subjects who perceive an improvement in his/her medical condition due to personal beliefs, rather than the drug treatment itself. Placebos play a significant role in medical research. Common placebos administered by the doctors include inert tablets (like sugar pills), shame surgery (placebo surgery), and other procedures opted by providing false information. Placebo effects are prominently driving the scientific research aiming to unravel the underlying neurobiological facets of action in pain relief, Parkinson's disease, depression etc. Placebos have been observed to impact the physiological changes in human body, such as heart rate, blood pressure accompanied by the chemical activity in the brain, in medical cases which involve pain, anxiety, fatigue, etc. The placebo effect projects the notable influence of perception and brain's role in the physical health of a human. However, the question of how placebos work has still not been answered with utmost surety by medical science. The paper proposes a unified platform for studying, factoring and visualizing the underlying effects of placebo/nocebo on human cell physiology, wherein the nocebo effect is the negative version of placebo effect.