EFFECT OF EVENING PRIMROSE ON PREMENSTRUAL SYNDROME: A RANDOMIZED CLINICAL TRIAL

Premenstrual syndrome is a set of physical and emotional psychological symptoms which occur periodically during the secretory phase of the menstrual period. This study was done to effect of Evening Primrose on premenstrual syndrome. This clinical double-blind study was conducted on 80 girls student suffered from premenstrual syndrome at Hamadan University of Medical Sciences, Hamadan, Iran. The samples were then randomly divided in two 40- member groups, Evening Primrose (1000 mg, 2 times per day) and placebo (2 times per day) groups. The subjects were received the therapeutic regimen for 2 months. Data collection tools were collected using questionnaires, daily symptom records (DSR) questionnaires and adverse drug reaction questionnaires of participants before and after intervention were registered and compared. Analyses were carried out by Chi-square, paired t-test using SPSS /21.The result showed that after intervention, severity of premenstrual syndrome was reduced in Evening Primrose group (61.45±21.25 to 21.38±9.05) (P<0.05). Findings revealed that taking Evening Primrose can reduce severity of premenstrual syndrome. So, regarding the little side complications, consumption of Evening Primrose has a useful effect on premenstrual syndrome. Key words: Premenstrual Syndrome, Evening Primrose, Iran