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An efficient approach to the synthesis of some novel heterocycles related to indoline moiety using [BMIm]Cl catalysis
Journal: Asian Journal of Green Chemistry (Vol.1, No. 2)Publication Date: 2017-10-01
Authors : Leila Youseftabar-Miri Hamide Hosseinjani-Pirdehi;
Page : 56-68
Keywords : Ionic liquid; Multi-compound reactions; Spirooxindole; Isatin; Pyrazole;
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Abstract
The combination of isatins, active methylene reagents and 4-phenylurazole/ phthalhydrazide in the presence of ionic liquid ([BMIm]Cl) as a solvent catalyst was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles. The features of this procedure were characterized by one-pot procedure, reasonable reaction times, fairly high yields, and simple isolation procedures. The ionic liquid can be easily separated and reused for several times.
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Last modified: 2018-01-28 14:25:45