Evaluation of the Oxidant/Antioxidant status, Nitric oxide and Adenosine deaminase levels in patients with Burn injury

Burn injury is among the most devastating of all injuries and is associated with the release of inflammatory mediators, including reactive oxygen species (ROS), reactive nitrogen species (RNS) and decreased immune system. There are conflicting results on association of oxidative stress, inflammation, and immune function in burn injury, so this study was conceptualized to evaluate the Oxidant/Antioxidant status in patients with burn injury, by measuring serum malondialdehyde (MDA) and superoxide dismutase (SOD) levels along with an inflammatory marker Serum Nitric oxide (NO) and a marker of immune status Adenosine deaminase (ADA). Material and Methods: In this cross-sectional study, 30 burn injury patients during the 1st week of burn injury were recruited as cases. 20 age and sex matched healthy individuals were included as controls. Serum MDA, SOD, NO and ADA were measured using spectrophotometer. Student’s unpaired t?test was used for analysis of data. p