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EVALUATION OF CARDIOTONIC ACTIVITY OF TECOMA STANS ON ISOLATED FROG’S HEART

Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.05, No. 02)

Publication Date:

Authors : ;

Page : 794-798

Keywords : Cardiotonic activity; Digoxin; Tecoma Stans; Isolated frog heart.;

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Abstract

Tecoma Stans, the yellow bells Plants belonging to the family Bignoniaceae. It height ranges from 2 to 4 meters. It is an important medicinal herb throughout India. Among all parts from Plant-seeds, roots and bark are the most important parts which are used medicinally. Present study was carried out to determine the cardiotonic activity by using infusion of Tecoma stanswith different dilutions & compared with cardiotonic activity of digoxin‐the life saving cardiotonic. The activity was tested by using isolated frog heart assembly. The present preliminary studies confirm the better cardiotonic act ivity of Tecoma Stan, than digoxin. Further studies can confirm the reduced toxicity & this will be the advantage of Tecoma stans, over digitalis. Thus, in future it will be interesting to isolate the active chemical constituents are responsible for the cardiotonic activity. Keywords: Cardiotonic activity, Digoxin, Tecoma Stans, Isolated frog heart.

Last modified: 2018-02-20 02:16:24