CHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITIES OF VERBESINA ENCELIOIDES
Journal: Indian Drugs (Vol.49, No. 1)Publication Date: 2012-01-28
Authors : Jain S. C. Jain R. Singh R.; Menghani E.;
Page : 38-42
Keywords : ;
- SYNTHESIS AND EVALUATION OF SOME SUBSTITUTED 2-AMINOTHIAZOLE DERIVATIVES FOR THEIR ANTITUBERCULAR, ANTIMICROBIAL & ANTIFUNGAL ACTIVITY
- Synthesis and Evaluation of some Substituted Aryl Oxadiazole and Mercapto Oxadiazole Derivatives for Antifungal, Antimicrobial and Antitubercular Activities
- SYNTHESIS AND EVALUATION OF SOME NEW SULPHUR, NITROGEN AND OXYGEN CONTAININGHETEROCYCLE THIADIAZOLOTRIAZOLE FOR ANTIBACTERIAL, ANTIFUNGAL & ANTITUBERCULAR ACTIVITY
- SYNTHETIC APPROACH TOWARDS PYRIMIDO [4, 5-B] QUINOLINE WITH 2-SUBSTITUTED DERIVATIVES AND STUDY OF ANTIMICROBIAL ACTIVITY
- Synthesis, chracterisation and antimicrobial activity of 1-[3/-(substituted phenyl)-5/-amino pyrimidine ] -3-(substituted phenyl)-5-(substituted phenyl)-2-pyrazolines as potential antimicrobial agent
Abstract
From the petroleum ether extract of flowers, betulin, friedelin and lupeol were isolated for the first time along with six other known compounds viz. n-triacontane, ester of ?-sitosterol, tricosyl alcohol,taraxasterol, ?-amyrin etc. During antibacterial screening, water extract of seeds showed appreciable activity (IZ 12 mm) against Pseudomonas aeruginosa. Similarly, in antifungal screening, chloroform extract of flowers (IZ 30 mm) and alcohol extract of roots (IZ 29 mm) exhibited very pronounced inhibitory activity against Tricophyton rubrum. High degree of free radical scavenging activity (RC50= 70 mcg) on DPPH assay of the pet. ether extract of roots was demonstrated among all the tested fractions.
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