A REVIEW ON TECHNOLOGIES EMPLOYED IN FORMULATION OF MOUTH DISSOLVING TABLETS

Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the mouth dissolving tablets with improved patient compliance and convenience. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. Mouth dissolving tablets overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in paediatric and geriatric patients. Mouth dissolving tablets can be formulated by using various technologies like lyophilization, direct compression, spray drying, molding, nanotization, mass extrusion, sublimation, cotton candy and phase transition technology along with various patented technologies like zydis,lyoc, flashtab, frosta, nanocrystal technology, wowtab, durasolv, orasolv advatab and flashdose technology. This review briefly describes about the various technologies which are used for the formulation of mouth dissolving tablets along with advantages and limitations of the technology. Keywords: Mouth dissolving tablets, Patented Technologies, Bioavailability