Prevalence of symptomatic peptic ulcer in diabetes mellitus patients at out patient department of government medical college and hospital in and around villupuram district

Introduction: A peptic ulcer is a sore that forms when digestive juices wear away the lining of the digestive system. A peptic ulcer can occur in the lining of the stomach, duodenum, or lower part of the esophagus. Symptoms can include indigestion-like pain, nausea, and weight loss. It is not uncommon for people to have a peptic ulcer and no symptoms at all. However, one of the most common symptoms of peptic ulcers is an indigestion-like pain. Diabetic shave increased the vulnerability of the gastric mucosa to various ulcerogens such as ethanol, ischemia/reperfusion, stress, and non-steroidal anti-inflammatory drugs. The notable changes that are often observed in patients with chronic diabetes mellitus are decreased gastric secretion (in response to insulin but not to either histamine or pentagastrin) and motility. The aim of the study: To assess the prevalence of gastric ulcer in diabetes mellitus patients who were attended Medicine OPD. Materials and methods: The study was conducted from April to August 2017 to explore the prevalence of peptic ulcer disease among the patients attended the Department of Medicine. Detailed information about the common signs and symptoms of peptic was analyzed with questioner regarding the prevalence of disease. Totally 50 patients with diabetes on medication with prone ulceration symptoms (25 –Group A) and (25-group B) patients with diabetes who were asymptomatic were considered as control group are taken in for the study. Results: After treating symptoms such as abdominal pain, nausea, abdominal bloating were completely relieved for group A subjects except for one case. Among 25 subjects with group B above symptoms were not completed seen. Out of treated subjects in the group A, 21subjects had a good appetite, free from the tar-like stool, abdominal pain, GERD reflex were improved in 22 cases after medication and diet control. Conclusion: The problems of the disease can be tackled through prevention and treatment which includes education, increasing awareness, reducing stress, and smoking and decreased intake of NSAIDs. H. Pylori prevalence was found to be high. Individuals who had a low educational level and NSAIDs consumers were under higher risk of infection than others. H. pylori infection appears not to be associated with diabetes.