PHARMACOLOGICAL EVALUATION FROM LEAVES EXTRACTS OF TRIGONELLA FOENUM-GRAECUM
Journal: IMPACT : International Journal of Research in Applied, Natural and Social Sciences ( IMPACT : IJRANSS ) (Vol.2, No. 4)Publication Date: 2014-04-30
Authors : SADIQ AZAM; SALMAN SHEHZADA; FARAH SHIREEN; SAJJAD FIDA; HAMAYUN KHATTAK; ZIAULLAH;
Page : 61-66
Keywords : Trigonella foenum-graecum; Antibacterial; Antifungal; Free Radical Scavenging; Phytotoxic; Hemagglutination;
Abstract
Medicinal herbal extracts are in vogue for over a century to cure human complications. Crude methanolic leaves extracts of competent herb Trigonella foenum-graecum were assessed for antibacterial, antifungal, free radical scavenging, hemagglutination and phytotoxic bioassay. Antibacterial bioassay was conducted via well diffusion protocol. And from the resulted zone of inhibition it was evinced that crude leaves extract possessed good activity against E.coli (47%), P. mirabilis (52%), B. cereus (60%) and P. aeruginosa (78%). Less antifungal aptitude against T. harizanum (30%) was validated. Rest of bacterial and fungal species was resistant. Less to moderate free radical scavenging capacity was demonstrated. Phytotoxic potentials at highest concentration was estimated i.e. 1000?g/ml (38%), manifesting moderate activity. No hemagglutination capacity was evidenced.
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