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REVIEW ON: GASTRORETENTIVE DRUG DELIVERY SYSTEM

Journal: INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND BIO SCIENCES (Vol.2, No. 1)

Publication Date:

Authors : ;

Page : 103-120

Keywords : Gastro retention; Floating; Stomach specific drug delivery.;

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Abstract

Conventional oral dosage forms pose low bioavailability problems due to their rapid gastric transition from stomach, especially in case of drugs which are less soluble at alkaline pH of intestine. Similarly, drugs which produce their local action in stomach get rapidly emptied and do not get enough residence time in stomach. So, frequency of dose administration in such cases is increased. To avoid this problem, various efforts have been made to prolong the retention time of drug delivery system. In this review, we will discuss about the various approaches to produce gastro retention of drug delivery system.

Last modified: 2013-02-25 02:22:29