Bacteriological profile of asymptomatic bacteriuria among diabetic patients

Introduction: Prevalence ofasymptomatic bacteriuria (ASB) among diabetic patients is high compared to patients without diabetes. The present study was aimed at determining the prevalence asymptomatic bacteriuria with diabetes and antimicrobial susceptibility pattern of isolated uropathogens. Materials and Methods: A prospective observational study was conducted in a rural tertiary care teaching hospital, in the department of microbiology to study the prevalence of ASB among patients with diabetes mellitus. Clean catch method was used to collect urine samples. All the urine specimens were processed according to standard microbiological procedures. Results: A total of 150 diabetic patients (81 females and 69 males) were included in the study. 25 urine specimens yielded significant bacterial growth and accounted for 16% Asymtomatic bacteriuria (ASB).Urine specimens collected from female 17 (11.3%) diabetic patients yielded growth predominatly. Urine samples collected from both male and female patients between the age group 51-60 (36%) years and 61-70 (24%) predominatly yielded the growth. In control group, Out of 150 urine samples from non diabetic patients, 7 urine specimens yielded growth and accounted for 4-6% asymptomatic bacteriuria. Escherichia coli was the predominant bacteria isolated in both study group and control group which accounted for 44% and 100% respectively. Conclusion: Asymptomatic bacteriuria among diabetic patients found to be high (16%) compared to healthy control group (4.6%). E,coli was the predominantly isolated bacteria from both diabetic patients and healthy control group. All Gram negative bacteria showed 100% susceptibility to imipenam. Good susceptibility was observed against both Gram positive and Gram negative bacteria by amikacin (90-100%) and nitrofurantoin (71-100%).