Management of endodontic-periodontic lesion with regenerative procedure: a split- mouth observational comparative case report

The proper diagnosis and treatment plan of endodontic-periodontic lesions is a clinical challenge. This lesion may have unusual presentation and may be present with absence of carious teeth, which makes it more difficult to diagnose. Though the radiographic investigations show periapical radiolucency, which suggests combined lesions, primary involvement is always difficult to diagnose. The treatment of such lesions is always difficult. Platelet-rich fibrin (PRF) is a concentrate from platelets widely used to accelerate soft and hard tissue healing. In addition, bioactive glass, an alloplastic bone graft, has a specific biological response, resulting in the formation of a bond between the tissues and graft thus facilitating bone healing. The purpose of this article is to present a case which was successfully treated by incorporating these novel grafting materials in regeneration of the intra-bony defects found in association with an endodontic-periodontic lesion.