Multiple juvenile xanthogranuloma: A rare case of having clinical appearance mimicking molluscum contagiosum or syringoma
Journal: Journal of General-Procedural Dermatology & Venereology Indonesia (Vol.1, No. 1)Publication Date: 2015-08-31
Authors : Heru Nugraha; Ridha Rosandi; Evelyn Lina Nainggolan; Githa Rahmayunita; Triana Agustin; Rahadi Rihatmadja; Siti Aisah Boediardja;
Page : 29-32
Keywords : Juvenile xanthogranuloma; clinicopathological correlation;
Abstract
Introduction: Juvenile xanthogranuloma (JXG) is an uncommon benign cutaneous fibrohistiocytic, self healing, class II non-Langerhan's cell histiocytosis (NLCH). JXG accounts for 80-90% of cases of NLCH. It occurs most commonly on the head and neck of infants and young children and resolves spontaneously. Case: A one year-old boy presented with asymptomatic, multiple yellowish, shiny, and firm nodules with telangiectasia on the surface, measuring around 1 centimeter in diameter, on the face, the trunk, the arms, and lower extremities. The first lesion appeared on the face 8 months prior to consultation then spread gradually to other areas. He was referred from another hospital and was diagnosed as molluscum contagiosum (MC) with differential diagnosis of syringoma. Enucleation had been performed but failed to produce the molluscum bodies. Initial histopathological examination provided the diagnosis of syringoma. The second histopathological examination showed dermal inflammatory cells consisting of eosinophils, lymphocytes, and histiocytes with marked foam cells and giant cells. Eccrine sweat glands were normal. Some lesions decreased in size at subsequent follow-ups; observation was advised until 3-6 years. Discussion : JXG should be suspected in cases with multiple yellowish nodules appearing in the first year of life. MC usually presents with whitish papules, whereas syringoma is more rarely appeared, presenting with yellow-to-brownish papules. Histopathological examination can easily differentiate the suspected diagnoses; however, selection of lesion, timing and complete clinical information was crucial in reaching the final diagnosis. In this case there was a good clinicopathological correlation that the diagnosis of JXG was made with certainty. There was no eye and other organ abnormalities.
Other Latest Articles
- A rare case of late onset reticulate acropigmentation of Kitamura without involvement of the palms and soles
- Systemic contact dermatitis due to nickel
- The evidence-based topical therapies for management of minor burns in outpatient clinic
- Prevalence of Mycoplasma hominis and Ureaplasma urealyticum infection in female sex workers and its association with douching: A study in East Jakarta, Indonesia using Mycoplasma System Plus
- Produksi dan Kualitas Beras Dua Varietas Padi Akibat Rebah dan Terendam
Last modified: 2018-04-26 11:57:21