DIABETIC FOOT ULCER; MANAGEMENT AND NOVEL TREATMENT APPROACHES

Objective: The present study is aimed to reveal the patho-physiology, epidemiology of serious complication associated with diabetes mellitus viz: Diabetic foot ulcer (DFU). In this study various conventional, herbal as well as novel treatment approaches are also focused. Another objective of the study is to provide beneficiary information to the diabetic patients who are at the risk of DFU. Review: DFU is one of the most serious complications associated with the diabetes mellitus. Characteristics of DFU are infection, leads to ulceration, and if preventive steps not taken then converted to gangrene and results in Amputation. Major contributors to the development of diabetic foot are neuropathy, poor circulation, Ischemia and susceptibility to infection. Diabetic foot ulcers occur in approximately 15% of patients with diabetes and of these, 14% to 24% of ulcers will end in amputation. Several therapies like Herbal therapy, Hyperbaric Oxygen Therapy, Low-level laser therapy, Operative Debridement are used to treat the DFU now days. Some novel approaches like larval therapy and maggot's therapy for treatment of DFU are also included in the study. Conclusion: On the basis of present review we have come to know DFU is a serious complication if serious concern is not taken. But if a care is taken, it is curable due to various treatment approaches according to the condition of wounds. But the primary approach is control of blood glucose. Keywords: Diabetic foot ulcer, Amputation, Novel approaches, Diabetes Mellitus