Pilomatrix carcinoma - pilomatrixoma: Two ends of the disease spectrum

Pilomatrixoma, pilomatrix carcinoma, are neoplasms of skin appendage with differentiation towards hair follicle matrix cells. They represent two ends of the spectrum with varying clinical and pathological characteristics. Pilomatrix carcinoma is a rare malignant neoplasm, having a tendency to recur locally, with a rare propensity for distant metastasis. There is a need to differentiate the two entity, for appropriate selection of treatment. We describe a case of a pilomatrixoma in a 62 year old gentleman over the right chest along with a review of pathology and treatment options.