BONE MINERAL DENSITY IN YOUNG FEMALES WITH JUVENILE IDIOPATHIC ARTHRITIS

Background: bone mineral density (BMD) in young adults with juvenile idiopathic arthritis (JIA) is affected by the presence of chronic systemic inflammation and the administration of glucocorticoids. Objective: the study of BMD in young adult females with JIA. Material and methods: 99 females aged 19-39 years were divided into two groups: group І – 59 healthy young females, group ІІ – 40 young females with JIA. BMD in different areas and their T- and Z-scores were evaluated by the X-ray densitometry. Results: the age of JIA onset was 11.16 ± 4.34 years, the disease duration averaged 11.9 ± 9.4 years. BMD, Tand Z-scores at L1-L4 (p <0.001), BMD and T-score (p <0.001) in the femoral neck (FN), BMD, T- and Z-scores (p <0.001) in the total body (TB) in group II were lower than in group I. In group II Z-score